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Michèle matriculated from Afrikaans Girls’ High School, Pretoria, in 1982, and went on to study Tourism at Pretoria Technicon and then Fine Arts at the University of Pretoria, where she was ultimately awarded an MA (Fine Arts) in 1993.
Michèle attracted nationwide interest in 1994 when the Rupert Art Foundation bought all of the available work on her first Solo Exhibition, including her Master’s degree installation ‘Kleursimfonie’, an extraordinary piece consisting of more than 300 A4 sized paintings exploring the theory of colour.. Following the purchase, Michèle was given the opportunity to travel with the panel for a year, exhibiting it and presenting lectures on colour to a wide variety of audiences. Once returned to the collection, it was put into storage until August 2015 when the panel was hung for two years at The Rupert Museum in Stellenbosch, and then again in 2020. It is currently being displayed at the Jan Rupert Art Centre in Graaff-Reinet, together with works developed in response to the panel, as part of an open call by The Rupert Museum.
Since 2004, Michèle has been living and working in Rosendal in the Eastern Free State, where her art is on permanent display at the Rosendal art gallery as well as the Michèle Nigrini Studio.
Collections include banks, corporates, museums, universities and private collections all over the world.